{"id":112095,"date":"2025-11-10T14:23:49","date_gmt":"2025-11-10T13:23:49","guid":{"rendered":"https:\/\/solidworldgroup.it\/non-categorizzato\/electrospider-creates-a-biomimetic-tracheal-model-3d-bioprinting-marks-a-new-step-towards-regenerative-medicine\/"},"modified":"2025-11-10T14:44:46","modified_gmt":"2025-11-10T13:44:46","slug":"electrospider-creates-a-biomimetic-tracheal-model-3d-bioprinting-marks-a-new-step-towards-regenerative-medicine","status":"publish","type":"post","link":"https:\/\/solidworldgroup.it\/en\/press-releases\/electrospider-creates-a-biomimetic-tracheal-model-3d-bioprinting-marks-a-new-step-towards-regenerative-medicine\/","title":{"rendered":"Electrospider creates a biomimetic tracheal model. 3D bioprinting marks a new step towards regenerative medicine"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-post\" data-elementor-id=\"112095\" class=\"elementor elementor-112095 elementor-112079\" data-elementor-post-type=\"post\">\n\t\t\t\t\t\t<section data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-section elementor-top-section elementor-element elementor-element-75e00620 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"75e00620\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-465304cd\" data-id=\"465304cd\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-35a3c541 elementor-widget elementor-widget-text-editor\" data-id=\"35a3c541\" data-element_type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<style>\/*! elementor - v3.19.0 - 29-01-2024 *\/\n.elementor-widget-text-editor.elementor-drop-cap-view-stacked .elementor-drop-cap{background-color:#69727d;color:#fff}.elementor-widget-text-editor.elementor-drop-cap-view-framed .elementor-drop-cap{color:#69727d;border:3px solid;background-color:transparent}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap{margin-top:8px}.elementor-widget-text-editor:not(.elementor-drop-cap-view-default) .elementor-drop-cap-letter{width:1em;height:1em}.elementor-widget-text-editor .elementor-drop-cap{float:left;text-align:center;line-height:1;font-size:50px}.elementor-widget-text-editor .elementor-drop-cap-letter{display:inline-block}<\/style>\t\t\t\t<p><em>Treviso, November 10, 2025 <\/em>\u2013 <strong>SolidWorld Group S.p.A.<\/strong>, listed on <strong>Euronext Growth Milan (ticker: S3D)<\/strong>, is an Italian technology group, leader in the integration of advanced 3D digital solutions and artificial intelligence, for the <strong>industrial, biomedical and defense sectors,<\/strong> marks a new step forward in the development of regenerative medicine.<\/p>\n<p>Thanks to <strong>Electrospider<\/strong>, the first Italian 3D bioprinter patented worldwide and developed by <strong>Bio3DPrinting<\/strong>, a company controlled by <strong>Bio3DModel <\/strong>and part of the SolidWorld Group, a proof of concept of a <strong>biomimetic tracheal scaffold<\/strong> has been created, capable of reproducing the topological complexity of human tissue and opening new perspectives for research applied to organ regeneration.<\/p>\n<p>This study represents a concrete example of collaboration between industry and academia, where the synergy between industrial know-how and academic research generates tangible results in the field of advanced biofabrication.<\/p>\n<p>Reproducing a <strong>biomimetic <\/strong><strong>trachea <\/strong>scaffold means creating a construct that faithfully mimics the structure and mechanical behavior of the natural organ. The trachea is, in fact, a complex organ composed of <strong>mucosa, muscle, and cartilage, <\/strong>which work together to maintain airway patency and allow the passage of air. <\/p>\n<p>Until now, the possibility of repairing or replacing damaged tracheal segments has been hindered by three main factors: the risk of graft <strong>rejection<\/strong>, the difficulty of achieving proper <strong>vascularization<\/strong>, and the <strong>anatomical complexity<\/strong> unique to each patient.<\/p>\n<p>The research conducted with Electrospider aims to overcome these obstacles, paving the way for personalized <strong>solutions to medium-sized tracheal defects<\/strong>, such as those resulting from prolonged<strong> intubations, trauma, or congenital malformations.<\/strong><\/p>\n<p>Thanks to its unique ability to <strong>combine multiple biofabrication techniques within a single bioprinting session<\/strong>, the system enables the biofabrication of three-dimensional structures that reproduce the <strong> natural organization of tissues<\/strong> and <strong>their mechanical behavio<\/strong>r.<\/p>\n<p>In the specific case of the trachea, <strong>Electrospider integrates three bioprinting technologies<\/strong>: <strong>electrospinning<\/strong>, for the production of micro- and nanofibers that mimic the extracellular matrix; the P<strong>neumatic Melt Extruder (PME)<\/strong>, which allows the deposition of thermoplastic polymers providing mechanical stability and shape to the scaffold; and the <strong>Photocuring Pneumatic Extruder (PPE)<\/strong>, which enables the controlled deposition of photosensitive materials\u2014such as specific hydrogels.<\/p>\n<p>\u201cElectrospider is one of the most ambitious technological challenges we have undertaken,\u201d said <strong>Roberto Rizzo, President and CEO of SolidWorld Group. <\/strong> \u201c<em>\u201cThe biomimetic tracheal patch we have created demonstrates the maturity of our platform and the Group\u2019s ability to connect industrial vision with advanced research. It is a concrete step toward next-generation bioprinting, uniting science, engineering, and social impact.\u201d <\/em><\/p>\n<p>The innovative character of the platform lies in its <strong>multi-function printing head<\/strong>, capable of combining up to <strong>five different printing technologies within the same biofabrication session. <\/strong><\/p>\n<p>This enables the processing of different materials at resolutions ranging from the millimeter to the nanometer scale, and, in perspective, the development of <strong>patches <\/strong>and <strong>complex organs fabricated in a single process<\/strong>, while ensuring high repeatability, quality, and productivity.<\/p>\n<p>Once the process is fully optimized, the patch can be replicated on a large scale, with minimal variation between production samples and significantly reduced fabrication time.<\/p>\n<p>The project originates from the PhD research of Alessandro Velletri, carried out at the University of Pisa and co-funded by Bio3DPrinting within the framework of PNRR programs dedicated to research and innovation in the biomedical field.<\/p>\n<p>Presented at the <strong>European Society for Biofabrication (ESB) Congress<\/strong> and at the<strong> Biofabrication 2025 Conference in Poland<\/strong>, it represents a significant milestone in Bio3DPrinting\u2019s research and development path and confirms the <strong>concrete potential <\/strong>of the Electrospider technology.<\/p>\n<p>The ability to <strong>bioprint physiologically relevant scaffolds<\/strong> opens new scenarios not only for in-vitro experimentation, but also paves the way for the <strong>future bioprinting of transplantable organs<\/strong>. The ultimate goal remains to contribute to the creation of increasingly realistic living models, capable of bridging the gap between scientific research and personalized transplantation. <\/p>\n<p><em>\u201cThis study marks a turning point in our journey,\u201d <\/em>added <strong>Aurora De Acutis, co-founder of Bio3DPrinting.<\/strong> \u201c<em>\u201cWith Electrospider, we have demonstrated that the synergistic combination of multiple bioprinting techniques sets the stage for the biofabrication of complex constructs capable of supporting the regeneration of organ portions, such as the trachea. Our goal remains to one day<strong> bioprint transplantable organs,<\/strong> but this first achievement already confirms the <strong>real and measurable potential<\/strong> of our technology.\u201d <\/em>.\u201d<\/p>\n<p>With its biomedical division, SolidWorld Group reaffirms its long-term vision: to <strong>build an Italian 3D bioprinting supply chain<\/strong> capable of competing internationally and bringing additive technologies to serve regenerative medicine.<\/p>\n<p style=\"text-align: center;\">***<\/p>\n<p><strong><em>SolidWorld Group S.p.A. <\/em><\/strong><em>listed on Euronext Growth Milan (<strong>ticker: S3D<\/strong>), is an <strong>Italian technology group <\/strong>leader in the integration of <strong>advanced 3D digital solutions and artificial intelligence<\/strong>, serving strategic and next-generation industrial sectors. Founded in the early 2000s by engineer Roberto Rizzo, the Group drives the transformation of manufacturing companies toward \u201cFactory 5.0\u201d through proprietary software and hardware technologies that make production processes faster, more sustainable, and more efficient. Comprising 10 companies, 14 locations 3 tech hubs, and over 178 employees SolidWorld serves more than 10,000 clients. Key innovations include Electrospider, a 3D bioprinter capable of replicating human tissues and organs. As of December 31, 2024, the Group recorded a Value of Production equal to Eur 66,2 million and an EBITDA of Eur 6.5 million.     <\/em><a href=\"http:\/\/www.solidworldgroup.it\/\"><em>www.solidworldgroup.it<\/em><\/a><\/p>\n<p><strong>CONTACTS<\/strong><br \/><strong><em>Investor Relations Manager<\/em><\/strong><br \/>Elisabetta Cammarata <br \/><a href=\"mailto:investor@solidworld.it\">investor@solidworld.it<\/a><\/p>\n<p><strong><em>IR &amp; Media Relations Advisor<\/em><br \/><\/strong><strong>Image Building Societ\u00e0 Benefit<br \/><\/strong><a href=\"mailto:solidworld@imagebuilding.it\">solidworld@imagebuilding.it <\/a><u>&#8211; <\/u>Tel. +39 02 89011300<\/p>\n<p><strong><em>Euronext Growth Advisor &amp; Specialist<br \/><\/em><\/strong>Integrae SIM | <a href=\"mailto:info@integraesim.it\">info@integraesim.it<\/a> | T: 02 80 50 61 60 | Piazza Castello, 24 Milano<\/p>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section data-particle_enable=\"false\" data-particle-mobile-disabled=\"false\" class=\"elementor-section elementor-top-section elementor-element elementor-element-f3cc055 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"f3cc055\" data-element_type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1302580\" data-id=\"1302580\" data-element_type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-66931f6 elementor-widget elementor-widget-html\" data-id=\"66931f6\" data-element_type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t<div class=\"elementor-widget-container\">\n\t\t\t<script charset=\"utf-8\" type=\"text\/javascript\" src=\"\/\/js.hsforms.net\/forms\/embed\/v2.js\"><\/script><script>hbspt.forms.create({\n    region: \"na1\",\n    portalId: \"7672778\",\n    formId: \"796bf688-0772-4904-9de7-b3fbde11157f\"\n  });\n<\/script>\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>Treviso, November 10, 2025 \u2013 SolidWorld Group S.p.A., listed on Euronext Growth Milan (ticker: S3D), is an Italian technology group, leader in the integration of advanced 3D digital solutions and artificial intelligence, for the industrial, biomedical and defense sectors, marks a new step forward in the development of regenerative medicine. Thanks to Electrospider, the first [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":112083,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[315],"tags":[],"class_list":["post-112095","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-press-releases"],"_links":{"self":[{"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/posts\/112095","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/comments?post=112095"}],"version-history":[{"count":3,"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/posts\/112095\/revisions"}],"predecessor-version":[{"id":112098,"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/posts\/112095\/revisions\/112098"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/media\/112083"}],"wp:attachment":[{"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/media?parent=112095"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/categories?post=112095"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/solidworldgroup.it\/en\/wp-json\/wp\/v2\/tags?post=112095"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}